6TYY
Hedgehog autoprocessing mutant D46H
Summary for 6TYY
| Entry DOI | 10.2210/pdb6tyy/pdb |
| Descriptor | Protein hedgehog (2 entities in total) |
| Functional Keywords | hedgehog autoprocessing doamin, signaling protein |
| Biological source | Drosophila melanogaster (Fruit fly) |
| Total number of polymer chains | 1 |
| Total formula weight | 15999.28 |
| Authors | Li, H.,Li, Z.,Wang, C.,Callahan, B.P. (deposition date: 2019-08-09, release date: 2019-11-20, Last modification date: 2023-10-11) |
| Primary citation | Zhao, J.,Ciulla, D.A.,Xie, J.,Wagner, A.G.,Castillo, D.A.,Zwarycz, A.S.,Lin, Z.,Beadle, S.,Giner, J.L.,Li, Z.,Li, H.,Banavali, N.,Callahan, B.P.,Wang, C. General Base Swap Preserves Activity and Expands Substrate Tolerance in Hedgehog Autoprocessing. J.Am.Chem.Soc., 141:18380-18384, 2019 Cited by PubMed: 31682419DOI: 10.1021/jacs.9b08914 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.36 Å) |
Structure validation
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