6TW5

Plasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-917

This is a non-PDB format compatible entry.

Summary for 6TW5

• Entry DOI: 10.2210/pdb6tw5/pdb
• Related: 5O6H
• Descriptor: Glycylpeptide N-tetradecanoyltransferase, 1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine, TETRADECANOYL-COA, ... (8 entities in total)
• Functional Keywords: myristoylation, malaria, indazole inhibitor, transferase
• Biological source: Plasmodium vivax
• Total number of polymer chains: 3
• Total formula weight: 141009.78

Authors

Brannigan, J.A. (deposition date: 2020-01-12, release date: 2021-07-21)

• Primary citation: Brannigan, J.A.; Plasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-917; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.55 Å)