6TW5
Plasmodium vivax N-myristoyltransferase with bound indazole inhibitor IMP-917
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (AAA, BBB, CCC) | Glycylpeptide N-tetradecanoyltransferase | polymer | 388 | 45369.9 | 3 | UniProt (A5K1A2) Pfam (PF01233) Pfam (PF02799) | Plasmodium vivax | |
| 2 | D, K, P (AAA, BBB, CCC) | 1-[5-[4-fluoranyl-2-[2-(1,3,5-trimethylpyrazol-4-yl)ethoxy]phenyl]-2~{H}-indazol-3-yl]-~{N},~{N}-dimethyl-methanamine | non-polymer | 421.5 | 3 | Chemie (9M2) | |||
| 3 | E, L, Q (AAA, BBB, CCC) | TETRADECANOYL-COA | non-polymer | 977.9 | 3 | Chemie (MYA) | |||
| 4 | F, M, R (AAA, BBB, CCC) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) | |||
| 5 | G, N, S (AAA, BBB, CCC) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 3 | Chemie (DMS) | |||
| 6 | H, O, T (AAA, BBB, CCC) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 7 | I, J, U (AAA, CCC) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 8 | V, W, X (AAA, BBB, CCC) | water | water | 18.0 | 1666 | Chemie (HOH) |
Sequence modifications
AAA, BBB, CCC: 27 - 410 (UniProt: A5K1A2)
| PDB | External Database | Details |
|---|---|---|
| Gly 23 | - | expression tag |
| Pro 24 | - | expression tag |
| His 25 | - | expression tag |
| Met 26 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 136109.7 | |
| Non-Polymers* | Number of molecules | 18 |
| Total formula weight | 4900.1 | |
| All* | Total formula weight | 141009.8 |
