6TP5

Crystal structure of human Transmembrane prolyl 4-hydroxylase

Summary for 6TP5

• Entry DOI: 10.2210/pdb6tp5/pdb
• Descriptor: Transmembrane prolyl 4-hydroxylase, CHLORIDE ION, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: prolyl-4-hydroxylase, 2-oxoglutarate-binding protein, transmembrane protein, ef-hand, double-stranded beta helix, iron-binding protein, calcium-binding protein, hidea syndrome, oxidoreductase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 102370.33

Authors

Myllykoski, M.,Sutinen, A.,Koski, M.K.,Kallio, J.P.,Raasakka, A.,Myllyharju, J.,Wierenga, R.K.,Koivunen, P. (deposition date: 2019-12-12, release date: 2020-12-23, Last modification date: 2024-01-24)

• Primary citation: Myllykoski, M.,Sutinen, A.,Koski, M.K.,Kallio, J.P.,Raasakka, A.,Myllyharju, J.,Wierenga, R.K.,Koivunen, P.; Structure of transmembrane prolyl 4-hydroxylase reveals unique organization of EF and dioxygenase domains.; J.Biol.Chem., 296:100197-100197, 2020; PubMed: 33334883; DOI: 10.1074/jbc.RA120.016542

Experimental method

X-RAY DIFFRACTION (2.25 Å)