6TI4
SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with PLP/D-Serine/Lys230 gem diamine complex
Summary for 6TI4
Entry DOI | 10.2210/pdb6ti4/pdb |
Descriptor | Serine hydroxymethyltransferase, GLYCEROL, (2~{R})-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-3-oxidanyl-propanoic acid, ... (5 entities in total) |
Functional Keywords | pyridoxal phosphate; x-ray crystallography; hydroxymethyltransferase; proton abstraction; tetrahydrofolate-independent, transferase |
Biological source | Streptococcus thermophilus |
Total number of polymer chains | 2 |
Total formula weight | 91004.81 |
Authors | Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I. (deposition date: 2019-11-21, release date: 2020-04-15, Last modification date: 2024-01-24) |
Primary citation | Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I. Crystal Structure of Y55S Serine Hydroxymethyltransferase variant from Streptococcus thermophilus in complex with gem-diamine intermediate of D-serine To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.93 Å) |
Structure validation
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