6TI4

SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with PLP/D-Serine/Lys230 gem diamine complex

Summary for 6TI4

• Entry DOI: 10.2210/pdb6ti4/pdb
• Descriptor: Serine hydroxymethyltransferase, GLYCEROL, (2~{R})-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-3-oxidanyl-propanoic acid, ... (5 entities in total)
• Functional Keywords: pyridoxal phosphate; x-ray crystallography; hydroxymethyltransferase; proton abstraction; tetrahydrofolate-independent, transferase
• Biological source: Streptococcus thermophilus
• Total number of polymer chains: 2
• Total formula weight: 91004.81

Authors

Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I. (deposition date: 2019-11-21, release date: 2020-04-15, Last modification date: 2024-01-24)

• Primary citation: Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I.; Crystal Structure of Y55S Serine Hydroxymethyltransferase variant from Streptococcus thermophilus in complex with gem-diamine intermediate of D-serine; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.93 Å)