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6TI4

SHMT from Streptococcus thermophilus Tyr55Ser variant in complex with PLP/D-Serine/Lys230 gem diamine complex

Summary for 6TI4
Entry DOI10.2210/pdb6ti4/pdb
DescriptorSerine hydroxymethyltransferase, GLYCEROL, (2~{R})-2-[[2-methyl-3-oxidanyl-5-(phosphonooxymethyl)pyridin-4-yl]methylamino]-3-oxidanyl-propanoic acid, ... (5 entities in total)
Functional Keywordspyridoxal phosphate; x-ray crystallography; hydroxymethyltransferase; proton abstraction; tetrahydrofolate-independent, transferase
Biological sourceStreptococcus thermophilus
Total number of polymer chains2
Total formula weight91004.81
Authors
Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I. (deposition date: 2019-11-21, release date: 2020-04-15, Last modification date: 2024-01-24)
Primary citationPetrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I.
Crystal Structure of Y55S Serine Hydroxymethyltransferase variant from Streptococcus thermophilus in complex with gem-diamine intermediate of D-serine
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.93 Å)
Structure validation

217705

PDB entries from 2024-03-27

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