6TGH
SHMT from Streptococcus thermophilus Tyr55Thr variant in complex with D-Serine both as external aldimine and as non-covalent complex
Summary for 6TGH
Entry DOI | 10.2210/pdb6tgh/pdb |
Descriptor | Serine hydroxymethyltransferase, SODIUM ION, L-Serine, N-[[3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]-4-pyridinyl]methylene], ... (6 entities in total) |
Functional Keywords | pyridoxal phosphate; x-ray crystallography; hydroxymethyltransferase; proton abstraction; tetrahydrofolate-independent, transferase |
Biological source | Streptococcus thermophilus |
Total number of polymer chains | 4 |
Total formula weight | 181218.89 |
Authors | Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I. (deposition date: 2019-11-15, release date: 2020-06-03, Last modification date: 2024-01-24) |
Primary citation | Petrillo, G.,Hernandez, K.,Bujons, J.,Clapes, P.,Uson, I. Structural insights into nucleophile substrate specificity in variants of N-Serine hydroxymethyltransferase from Streptococcus thermophilus To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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