6TGB

CryoEM structure of the binary DOCK2-ELMO1 complex

Summary for 6TGB

Entry DOI	10.2210/pdb6tgb/pdb
EMDB information	10497
Descriptor	Dedicator of cytokinesis protein 2, Engulfment and cell motility protein 1 (2 entities in total)
Functional Keywords	guanine nucleotide exchange factor, cytoskeleton, actin, cryoem, signaling protein
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	475696.36
Authors	Chang, L.,Yang, J.,Chang, J.H.,Zhang, Z.,Boland, A.,McLaughlin, S.H.,Abu-Thuraia, A.,Killoran, R.C.,Smith, M.J.,Cote, J.F.,Barford, D. (deposition date: 2019-11-15, release date: 2020-07-29, Last modification date: 2024-05-22)
Primary citation	Chang, L.,Yang, J.,Jo, C.H.,Boland, A.,Zhang, Z.,McLaughlin, S.H.,Abu-Thuraia, A.,Killoran, R.C.,Smith, M.J.,Cote, J.F.,Barford, D. Structure of the DOCK2-ELMO1 complex provides insights into regulation of the auto-inhibited state. Nat Commun, 11:3464-3464, 2020 Cited by PubMed: 32651375 DOI: 10.1038/s41467-020-17271-9 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (5.5 Å)

Structure validation