Crystal structure of the Kelch domain in complex with 11 amino acid peptide (model of the ETGE loop)

This is a large structure.

Summary for 6TG8

DescriptorKelch-like ECH-associated protein 1, VAL-ILE-ASN-PRO-GLU-THR-GLY-GLU-GLN-ILE-GLN, SODIUM ION, ... (4 entities in total)
Functional Keywordscomplex, beta proteins, kelch motif, ligase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight32833.61
Kekez, I.,Matic, S.,Tomic, S.,Matkovic-Calogovic, D. (deposition date: 2019-11-15, release date: 2020-09-16, Last modification date: 2020-09-23)
Primary citation
Matic, S.,Kekez, I.,Tomin, M.,Bogar, F.,Supljika, F.,Kazazic, S.,Hanic, M.,Jha, S.,Brkic, H.,Bourgeois, B.,Madl, T.,Gruber, K.,Macheroux, P.,Matkovic-Calogovic, D.,Matovina, M.,Tomic, S.
Binding of dipeptidyl peptidase III to the oxidative stress cell sensor Kelch-like ECH-associated protein 1 is a two-step process.
J.Biomol.Struct.Dyn., :1-12, 2020
PubMed: 32811353 (PDB entries with the same primary citation)
DOI: 10.1080/07391102.2020.1804455
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2576 0.3% 5.3% 5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-09-30