6TG8

Crystal structure of the Kelch domain in complex with 11 amino acid peptide (model of the ETGE loop)

This is a large structure.

Summary for 6TG8

DescriptorKelch-like ECH-associated protein 1, VAL-ILE-ASN-PRO-GLU-THR-GLY-GLU-GLN-ILE-GLN, SODIUM ION, ... (4 entities in total)
Functional Keywordscomplex, beta proteins, kelch motif, ligase
Biological sourceHomo sapiens (Human)
Total number of polymer chains2
Total molecular weight32833.61
Authors
Kekez, I.,Matic, S.,Tomic, S.,Matkovic-Calogovic, D. (deposition date: 2019-11-15, release date: 2020-09-16, Last modification date: 2020-09-23)
Primary citation
Matic, S.,Kekez, I.,Tomin, M.,Bogar, F.,Supljika, F.,Kazazic, S.,Hanic, M.,Jha, S.,Brkic, H.,Bourgeois, B.,Madl, T.,Gruber, K.,Macheroux, P.,Matkovic-Calogovic, D.,Matovina, M.,Tomic, S.
Binding of dipeptidyl peptidase III to the oxidative stress cell sensor Kelch-like ECH-associated protein 1 is a two-step process.
J.Biomol.Struct.Dyn., :1-12, 2020
PubMed: 32811353 (PDB entries with the same primary citation)
DOI: 10.1080/07391102.2020.1804455
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.75 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2576 0.3% 5.3% 5.0%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
169436
PDB entries from 2020-09-30