Crystal structure of Escherichia coli Orotate Phosphoribosyltransferase in complex with Orotic acid 1.60 Angstrom resolution

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Summary for 6TAJ

DescriptorOrotate phosphoribosyltransferase, OROTIC ACID, GLYCEROL, ... (4 entities in total)
Functional Keywordsorotate phosphoribosyltransferase (oprt), orotic acid, transferase
Biological sourceEscherichia coli (strain K12)
Total number of polymer chains2
Total molecular weight47686.31
Navas-Yuste, S.,Lopez-Estepa, M.,Gomez, S.,Fernandez, F.J.,Vega, M.C. (deposition date: 2019-10-29, release date: 2020-11-18)
Primary citation
Roca, M.,Navas-Yuste, S.,Zinovjev, K.,Lopez-Estepa, M.,Gomez, S.,Fernandez, F.J.,Vega, M.C.,Tunon, I.
Elucidating the Catalytic Reaction Mechanism of Orotate Phosphoribosyltransferase by means of the Adaptive String Method
To Be Published,
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers20 0.3% 4.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25