6TA6
MexAB assembly of the Pseudomonas MexAB-OprM efflux pump reconstituted in nanodiscs
Summary for 6TA6
Entry DOI | 10.2210/pdb6ta6/pdb |
Related | 6TA5 |
EMDB information | 10395 |
Descriptor | Outer membrane protein OprM, MexA family multidrug efflux RND transporter periplasmic adaptor subunit, Efflux pump membrane transporter (3 entities in total) |
Functional Keywords | transporter, efflux, proton motive force, bacterial resistance, antimicrobial protein |
Biological source | Pseudomonas aeruginosa More |
Total number of polymer chains | 12 |
Total formula weight | 733105.16 |
Authors | Glavier, M.,Schoehn, G.,Taveau, J.C.,Phan, G.,Daury, L.,Lambert, O.,Broutin, I. (deposition date: 2019-10-29, release date: 2020-09-16, Last modification date: 2024-05-15) |
Primary citation | Glavier, M.,Puvanendran, D.,Salvador, D.,Decossas, M.,Phan, G.,Garnier, C.,Frezza, E.,Cece, Q.,Schoehn, G.,Picard, M.,Taveau, J.C.,Daury, L.,Broutin, I.,Lambert, O. Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex. Nat Commun, 11:4948-4948, 2020 Cited by PubMed: 33009415DOI: 10.1038/s41467-020-18770-5 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.2 Å) |
Structure validation
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