6T92
NAD+-dependent fungal formate dehydrogenase from Chaetomium thermophilum: A complex of N120C mutant protein with the reduced form of the cofactor NADH and the substrate formate at a secondary site.
This is a non-PDB format compatible entry.
Summary for 6T92
Entry DOI | 10.2210/pdb6t92/pdb |
Descriptor | Formate dehydrogenase, DI(HYDROXYETHYL)ETHER, 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, ... (6 entities in total) |
Functional Keywords | nad+, cytosolic protein |
Biological source | Chaetomium thermophilum (strain DSM 1495 / CBS 144.50 / IMI 039719) |
Total number of polymer chains | 4 |
Total formula weight | 186408.71 |
Authors | Isupov, M.N.,Yelmazer, B.,De Rose, S.A.,Littlechild, J.A. (deposition date: 2019-10-25, release date: 2020-11-18, Last modification date: 2024-01-24) |
Primary citation | Yilmazer, B.,Isupov, M.N.,De Rose, S.A.,Bulut, H.,Benninghoff, J.C.,Binay, B.,Littlechild, J.A. Structural insights into the NAD + -dependent formate dehydrogenase mechanism revealed from the NADH complex and the formate NAD + ternary complex of the Chaetomium thermophilum enzyme. J.Struct.Biol., 212:107657-107657, 2020 Cited by PubMed: 33148525DOI: 10.1016/j.jsb.2020.107657 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.12 Å) |
Structure validation
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