6T7Q
Human Aldose Reductase Mutant L301A in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid)
Summary for 6T7Q
Entry DOI | 10.2210/pdb6t7q/pdb |
Descriptor | Aldo-keto reductase family 1 member B1, 3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid, CITRIC ACID, ... (5 entities in total) |
Functional Keywords | oxidoreductase, l301a mutant, sar_061 ligand, transient binding pocket |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 37139.09 |
Authors | Hubert, L.-S.,Ley, M.,Heine, A.,Klebe, G. (deposition date: 2019-10-23, release date: 2020-11-18, Last modification date: 2024-01-24) |
Primary citation | Hubert, L.-S.,Ley, M.,Scheer, F.,Diederich, W.,Heine, A.,Klebe, G. Human Aldose Reductase Mutant L301A in Complex with a Ligand with an IDD Structure (3-({[2-(carboxymethoxy)-4-fluorobenzoyl]amino}methyl)benzoic acid) To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.01 Å) |
Structure validation
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