6T5Y
Crystal structure of AmpC from E.coli with Zidebactam (WCK 5107)
Summary for 6T5Y
Entry DOI | 10.2210/pdb6t5y/pdb |
Descriptor | Beta-lactamase, DI(HYDROXYETHYL)ETHER, (2S,5R)-1-formyl-N'-[(3R)-piperidine-3-carbonyl]-5-[(sulfooxy)amino]piperidine-2-carbohydrazide, ... (6 entities in total) |
Functional Keywords | beta lactamase, antibiotic resistance, diazabicyclooctane, dbo, hydrolase |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 1 |
Total formula weight | 40188.32 |
Authors | Lang, P.A.,Leissing, T.M.,Schofield, C.J.,Brem, J. (deposition date: 2019-10-17, release date: 2020-11-18, Last modification date: 2024-01-24) |
Primary citation | Lang, P.A.,Leissing, T.M.,Page, M.G.P.,Schofield, C.J.,Brem, J. Structural Investigations of the Inhibition of Escherichia coli AmpC beta-Lactamase by Diazabicyclooctanes. Antimicrob.Agents Chemother., 65:-, 2021 Cited by PubMed: 33199391DOI: 10.1128/AAC.02073-20 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.3 Å) |
Structure validation
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