6T1Z

LmrP from L. lactis, in an outward-open conformation, bound to Hoechst 33342

Summary for 6T1Z

Entry DOI	10.2210/pdb6t1z/pdb
Descriptor	LmrP integral membrane protein, 2'-(4-ETHOXYPHENYL)-5-(4-METHYL-1-PIPERAZINYL)-2,5'-BI-BENZIMIDAZOLE, 1,2-DIMYRISTOYL-SN-GLYCERO-3-PHOSPHATE, ... (6 entities in total)
Functional Keywords	transmembrane multidrug transporter, transport protein
Biological source	Lactococcus lactis
Total number of polymer chains	1
Total formula weight	48026.93
Authors	Hutchin, A.,Debruycker, V.,Masureel, M.,Legrand, P.,Remaut, H.,Govaerts, C. (deposition date: 2019-10-07, release date: 2020-07-29, Last modification date: 2021-02-10)
Primary citation	Debruycker, V.,Hutchin, A.,Masureel, M.,Ficici, E.,Martens, C.,Legrand, P.,Stein, R.A.,Mchaourab, H.S.,Faraldo-Gomez, J.D.,Remaut, H.,Govaerts, C. An embedded lipid in the multidrug transporter LmrP suggests a mechanism for polyspecificity. Nat.Struct.Mol.Biol., 27:829-835, 2020 Cited by PubMed: 32719456 DOI: 10.1038/s41594-020-0464-y PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation