6SZW
Asymmetric complex of Factor XII and kininogen with gC1qR/C1QBP/P32 is governed by allostery
Summary for 6SZW
Entry DOI | 10.2210/pdb6szw/pdb |
Descriptor | Complement component 1 Q subcomponent-binding protein, mitochondrial, Coagulation factor XII, ZINC ION, ... (4 entities in total) |
Functional Keywords | contact activation, blood clotting |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 4 |
Total formula weight | 80136.06 |
Authors | Kaira, B.G.,Emsley, J. (deposition date: 2019-10-02, release date: 2020-07-22, Last modification date: 2024-01-24) |
Primary citation | Kaira, B.G.,Slater, A.,McCrae, K.R.,Dreveny, I.,Sumya, U.,Mutch, N.J.,Searle, M.,Emsley, J. Factor XII and kininogen asymmetric assembly with gC1qR/C1QBP/P32 is governed by allostery. Blood, 136:1685-1697, 2020 Cited by PubMed: 32559765DOI: 10.1182/blood.2020004818 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.14 Å) |
Structure validation
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