Summary for 6SYP
Entry DOI | 10.2210/pdb6syp/pdb |
Descriptor | Dihydroorotate dehydrogenase, FLAVIN MONONUCLEOTIDE, OROTIC ACID, ... (6 entities in total) |
Functional Keywords | dihydroorotate dehydrogenase inhibitor complex, structural genomics, structural genomics consortium, sgc, oxidoreductase |
Biological source | Homo sapiens |
Total number of polymer chains | 1 |
Total formula weight | 44041.10 |
Authors | Kraemer, A.,Janin, Y.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-09-30, release date: 2019-10-09, Last modification date: 2024-01-24) |
Primary citation | Kramer, A.,Kurz, C.G.,Berger, B.T.,Celik, I.E.,Tjaden, A.,Greco, F.A.,Knapp, S.,Hanke, T. Optimization of pyrazolo[1,5-a]pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor Eur.J.Med.Chem., 208:112770-, 2020 Cited by DOI: 10.1016/j.ejmech.2020.112770PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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