6SY1
Crystal structure of the human 2-oxoadipate dehydrogenase DHTKD1 (E1)
Summary for 6SY1
Entry DOI | 10.2210/pdb6sy1/pdb |
Descriptor | Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial, THIAMINE DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total) |
Functional Keywords | dehydrogenase, transketolase, thiamine pyrophosphate, mg, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 202775.75 |
Authors | Bezerra, G.A.,Foster, W.,Shrestha, L.,Pena, I.A.,Coker, J.,Kolker, S.,Nicola, B.B.,von Delft, F.,Edwards, A.,Arrowsmith, C.,Bountra, C.,Yue, W.W.,Structural Genomics Consortium (SGC) (deposition date: 2019-09-26, release date: 2020-06-24, Last modification date: 2024-01-24) |
Primary citation | Bezerra, G.A.,Foster, W.R.,Bailey, H.J.,Hicks, K.G.,Sauer, S.W.,Dimitrov, B.,McCorvie, T.J.,Okun, J.G.,Rutter, J.,Kolker, S.,Yue, W.W. Crystal structure and interaction studies of human DHTKD1 provide insight into a mitochondrial megacomplex in lysine catabolism. Iucrj, 7:693-706, 2020 Cited by PubMed: 32695416DOI: 10.1107/S205225252000696X PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.87 Å) |
Structure validation
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