6ST2

Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs

Summary for 6ST2

Entry DOI	10.2210/pdb6st2/pdb
Descriptor	Bcl-2-like protein 1, Affimer AF6, SULFATE ION, ... (4 entities in total)
Functional Keywords	affimer, protein binding
Biological source	Homo sapiens (Human) More
Total number of polymer chains	4
Total formula weight	56629.52
Authors	Hobor, F.,Miles, J.A.,Trinh, C.H.,Taylor, J.,Tiede, C.,Rowell, P.R.,Jackson, B.,Nadat, F.,Kyle, H.F.,Wicky, B.I.M.,Clarke, J.,Tomlinson, D.C.,Wilson, A.J.,Edwards, T.A. (deposition date: 2019-09-09, release date: 2020-09-30, Last modification date: 2024-01-24)
Primary citation	Miles, J.A.,Hobor, F.,Trinh, C.H.,Taylor, J.,Tiede, C.,Rowell, P.R.,Jackson, B.R.,Nadat, F.A.,Ramsahye, P.,Kyle, H.F.,Wicky, B.I.M.,Clarke, J.,Tomlinson, D.C.,Wilson, A.J.,Edwards, T.A. *Selective Affimers Recognise the BCL-2 Family Proteins BCL-x L and MCL-1 through Noncanonical Structural Motifs.** Chembiochem, 22:232-240, 2021 Cited by PubMed: 32961017 DOI: 10.1002/cbic.202000585 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.79 Å)

Structure validation