6ST2

Selective Affimers Recognize BCL-2 Family Proteins Through Non-Canonical Structural Motifs

6ST2 の概要

• エントリーDOI: 10.2210/pdb6st2/pdb
• 分子名称: Bcl-2-like protein 1, Affimer AF6, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: affimer, protein binding
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 56629.52

構造登録者

Hobor, F.,Miles, J.A.,Trinh, C.H.,Taylor, J.,Tiede, C.,Rowell, P.R.,Jackson, B.,Nadat, F.,Kyle, H.F.,Wicky, B.I.M.,Clarke, J.,Tomlinson, D.C.,Wilson, A.J.,Edwards, T.A. (登録日: 2019-09-09, 公開日: 2020-09-30, 最終更新日: 2024-01-24)

• 主引用文献: Miles, J.A.,Hobor, F.,Trinh, C.H.,Taylor, J.,Tiede, C.,Rowell, P.R.,Jackson, B.R.,Nadat, F.A.,Ramsahye, P.,Kyle, H.F.,Wicky, B.I.M.,Clarke, J.,Tomlinson, D.C.,Wilson, A.J.,Edwards, T.A.; Selective Affimers Recognise the BCL-2 Family Proteins BCL-x L and MCL-1 through Noncanonical Structural Motifs*.; Chembiochem, 22:232-240, 2021; PubMed: 32961017; DOI: 10.1002/cbic.202000585

実験手法

X-RAY DIFFRACTION (1.79 Å)