6SSU

Crystal structure of Human Microsomal Glutathione S-Transferase 2 in complex with co-substrate Glutathione

Summary for 6SSU

Entry DOI	10.2210/pdb6ssu/pdb
Descriptor	Microsomal glutathione S-transferase 2, (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, GLUTATHIONE, ... (5 entities in total)
Functional Keywords	er membrane protein, glutathione transferase, mapeg, mgst2, integral membrane enzyme, transferase
Biological source	Homo sapiens (Human)
Total number of polymer chains	3
Total formula weight	53785.96
Authors	Thulasingam, M.,Haeggstrom, J.Z. (deposition date: 2019-09-09, release date: 2021-02-03, Last modification date: 2024-01-24)
Primary citation	Thulasingam, M.,Orellana, L.,Nji, E.,Ahmad, S.,Rinaldo-Matthis, A.,Haeggstrom, J.Z. Crystal structures of human MGST2 reveal synchronized conformational changes regulating catalysis. Nat Commun, 12:1728-1728, 2021 Cited by PubMed: 33741927 DOI: 10.1038/s41467-021-21924-8 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.499 Å)

Structure validation