6SSP

Structure of the pentameric ligand-gated ion channel ELIC in complex with a NAM nanobody

Summary for 6SSP

• Entry DOI: 10.2210/pdb6ssp/pdb
• Related: 6SSI
• Descriptor: Cys-loop ligand-gated ion channel, NANOBODY 21, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: elic, cys-loop receptor, nanobody, pentameric ligand gated ion channel, transport protein
• Biological source: Dickeya chrysanthemi (Pectobacterium chrysanthemi); More
• Total number of polymer chains: 12
• Total formula weight: 400443.73

Authors

Ulens, C.,Brams, M.,Evans, G.L.,Spurny, R.,Govaerts, C.,Pardon, E.,Steyaert, J. (deposition date: 2019-09-09, release date: 2020-02-12, Last modification date: 2024-01-24)

• Primary citation: Brams, M.,Govaerts, C.,Kambara, K.,Price, K.L.,Spurny, R.,Gharpure, A.,Pardon, E.,Evans, G.L.,Bertrand, D.,Lummis, S.C.,Hibbs, R.E.,Steyaert, J.,Ulens, C.; Modulation of the Erwinia ligand-gated ion channel (ELIC) and the 5-HT 3 receptor via a common vestibule site.; Elife, 9:-, 2020; PubMed: 31990273; DOI: 10.7554/eLife.51511

Experimental method

X-RAY DIFFRACTION (3.25 Å)