6SQF

Crystal structure of CREBBP bromodomain complexed with LB32A

Summary for 6SQF

• Entry DOI: 10.2210/pdb6sqf/pdb
• Descriptor: CREB-binding protein, ~{N}-[3-[[5-ethanoyl-2-[2-(2-oxa-6-azaspiro[3.3]heptan-6-yl)ethoxy]phenyl]carbamoyl]-5-(1-methylpyrazol-3-yl)phenyl]furan-2-carboxamide (3 entities in total)
• Functional Keywords: inhibitor, complex, crebbp, bromodomain, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 14792.96

Authors

Bedi, R.K.,Laul, E.,Nevado, C.,Caflisch, A. (deposition date: 2019-09-03, release date: 2020-09-30, Last modification date: 2024-05-15)

• Primary citation: Bedi, R.K.,Laul, E.,Nevado, C.,Caflisch, A.; Crystal structure of CREBBP bromodomain complexed with LB32A; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.006 Å)