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6SQF

Crystal structure of CREBBP bromodomain complexed with LB32A

Functional Information from GO Data
ChainGOidnamespacecontents
A0004402molecular_functionhistone acetyltransferase activity
A0006355biological_processregulation of DNA-templated transcription
Functional Information from PDB Data
site_idAC1
Number of Residues17
Detailsbinding site for residue LTW A 1201
ChainResidue
APRO1106
AVAL1174
APHE1177
ASER1179
AHOH1320
AHOH1348
AHOH1372
AHOH1393
AHOH1415
ALEU1109
APRO1110
AGLN1113
AVAL1115
ALEU1120
ATRP1165
AASN1168
AARG1173

Functional Information from PROSITE/UniProt
site_idPS00633
Number of Residues60
DetailsBROMODOMAIN_1 Bromodomain signature. SlpFrqpvDpqllgipDYFdiVknpMdlstIkrkldtgq..Yqepwqyvddvwl.MfnNAwlY
ChainResidueDetails
ASER1108-TYR1167

223790

PDB entries from 2024-08-14

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