6SQ1

Crystal structure of cAMP-dependent Protein Kinase A (CHO PKA) in complex with Aminofasudil

Summary for 6SQ1

• Entry DOI: 10.2210/pdb6sq1/pdb
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, (4S)-2-METHYL-2,4-PENTANEDIOL, 5-(1,4-diazepan-1-ylsulfonyl)isoquinolin-1-amine, ... (5 entities in total)
• Functional Keywords: phosphotransferase, signalling pathways, glycogen metabolism, serine/threonine kinase, transferase
• Biological source: Cricetulus griseus (Chinese hamster)
• Total number of polymer chains: 1
• Total formula weight: 41812.76

Authors

Oebbeke, M.,Siefker, C.,Heine, A.,Klebe, G. (deposition date: 2019-09-03, release date: 2020-09-30, Last modification date: 2024-11-20)

• Primary citation: Oebbeke, M.,Wienen-Schmidt, B.,Gerber, H.-D.,Heine, A.,Klebe, G.; A crystallographic study of cAMP-dependent Protein Kinase A in complex with different Fasudil-derivatives; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.49 Å)