6SIV

Structure of HPV16 E6 oncoprotein in complex with mutant IRF3 LxxLL motif

Summary for 6SIV

• Entry DOI: 10.2210/pdb6siv/pdb
• Related: 4GIZ
• Related PRD ID: PRD_900030
• Descriptor: Maltose/maltodextrin-binding periplasmic protein,Interferon regulatory factor 3, Protein E6, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... (5 entities in total)
• Functional Keywords: hpv16 e6 protein, irf3 mutant, lxxll motif, viral protein
• Biological source: Escherichia coli (strain K12); More
• Total number of polymer chains: 2
• Total formula weight: 61202.99

Authors

Suarez, I.P.,Cousido-Siah, A.,Bonhoure, A.,Mitschler, A.,Podjarny, A.,Trave, G. (deposition date: 2019-08-12, release date: 2019-08-21, Last modification date: 2024-06-19)

• Primary citation: Poirson, J.,Suarez, I.P.,Cousido-Siah, A.,Forster, A.,Chebaro, Y.,Mitschler, A.,Straub, M.,Altschuh, D.,Podjarny, A.,Trave, G.,Masson, M.; Deciphering the molecular and structural interaction between IRF3 and HPV16 E6; To be published,

Experimental method

X-RAY DIFFRACTION (1.752 Å)