6SFO
MAPK14 with bound inhibitor SR-318
Summary for 6SFO
Entry DOI | 10.2210/pdb6sfo/pdb |
Descriptor | Mitogen-activated protein kinase 14, SODIUM ION, 5-azanyl-~{N}-[[4-(3-cyclohexylpropylcarbamoyl)phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide, ... (5 entities in total) |
Functional Keywords | kinase inhibitor p38a, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 41969.88 |
Authors | Schroeder, M.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-08-01, release date: 2019-09-11, Last modification date: 2024-01-24) |
Primary citation | Schroeder, M.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) MAPK14 with bound inhibitor SR-318 To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.75 Å) |
Structure validation
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