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6SFO

MAPK14 with bound inhibitor SR-318

Summary for 6SFO
Entry DOI10.2210/pdb6sfo/pdb
DescriptorMitogen-activated protein kinase 14, SODIUM ION, 5-azanyl-~{N}-[[4-(3-cyclohexylpropylcarbamoyl)phenyl]methyl]-1-phenyl-pyrazole-4-carboxamide, ... (5 entities in total)
Functional Keywordskinase inhibitor p38a, structural genomics, structural genomics consortium, sgc, transferase
Biological sourceHomo sapiens (Human)
Total number of polymer chains1
Total formula weight41969.88
Authors
Schroeder, M.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-08-01, release date: 2019-09-11, Last modification date: 2024-01-24)
Primary citationSchroeder, M.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC)
MAPK14 with bound inhibitor SR-318
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.75 Å)
Structure validation

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