6SCJ

The structure of human thyroglobulin

Summary for 6SCJ

• Entry DOI: 10.2210/pdb6scj/pdb
• EMDB information: 10141
• Descriptor: Thyroglobulin, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
• Functional Keywords: thyroglobulin, thyroid, thyroid hormones, tri-iodo-thyronine, thyroxine, hormone
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 617949.01

Authors

Coscia, F.,Turk, D.,Lowe, J. (deposition date: 2019-07-24, release date: 2020-02-12, Last modification date: 2020-07-29)

• Primary citation: Coscia, F.,Taler-Vercic, A.,Chang, V.T.,Sinn, L.,O'Reilly, F.J.,Izore, T.,Renko, M.,Berger, I.,Rappsilber, J.,Turk, D.,Lowe, J.; The structure of human thyroglobulin.; Nature, 578:627-630, 2020; PubMed: 32025030; DOI: 10.1038/s41586-020-1995-4

Experimental method

ELECTRON MICROSCOPY (3.6 Å)