dAb3/HOIP-RBR apo structure

Summary for 6SC6

DescriptorE3 ubiquitin-protein ligase RNF31, Single domain antibody, ZINC ION, ... (6 entities in total)
Functional Keywordshuman single domain antibody, hoip, rbr, ligase
Biological sourceHomo sapiens (Human)
Total number of polymer chains3
Total molecular weight70468.03
Tsai, Y.-C.I.,House, D.,Rittinger, K. (deposition date: 2019-07-23, release date: 2019-11-27, Last modification date: 2020-01-29)
Primary citation
Tsai, Y.I.,Johansson, H.,Dixon, D.,Martin, S.,Chung, C.W.,Clarkson, J.,House, D.,Rittinger, K.
Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases.
Cell Chem Biol, 27:83-, 2020
PubMed: 31813847 (PDB entries with the same primary citation)
DOI: 10.1016/j.chembiol.2019.11.007
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2473 0.2% 1.8% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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