6SC6

dAb3/HOIP-RBR apo structure

Summary for 6SC6

DescriptorE3 ubiquitin-protein ligase RNF31, Single domain antibody, ZINC ION, ... (6 entities in total)
Functional Keywordshuman single domain antibody, hoip, rbr, ligase
Biological sourceHomo sapiens (Human)
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Total number of polymer chains3
Total molecular weight70468.03
Authors
Tsai, Y.-C.I.,House, D.,Rittinger, K. (deposition date: 2019-07-23, release date: 2019-11-27, Last modification date: 2020-01-29)
Primary citation
Tsai, Y.I.,Johansson, H.,Dixon, D.,Martin, S.,Chung, C.W.,Clarkson, J.,House, D.,Rittinger, K.
Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases.
Cell Chem Biol, 27:83-, 2020
PubMed: 31813847 (PDB entries with the same primary citation)
DOI: 10.1016/j.chembiol.2019.11.007
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.25 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2473 0.2% 1.8% 2.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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