6SC6

dAb3/HOIP-RBR apo structure

Summary for 6SC6

Entry DOI	10.2210/pdb6sc6/pdb
Descriptor	E3 ubiquitin-protein ligase RNF31, Single domain antibody, ZINC ION, ... (6 entities in total)
Functional Keywords	human single domain antibody, hoip, rbr, ligase
Biological source	Homo sapiens (Human) More
Total number of polymer chains	3
Total formula weight	70468.03
Authors	Tsai, Y.-C.I.,House, D.,Rittinger, K. (deposition date: 2019-07-23, release date: 2019-11-27, Last modification date: 2024-01-24)
Primary citation	Tsai, Y.I.,Johansson, H.,Dixon, D.,Martin, S.,Chung, C.W.,Clarkson, J.,House, D.,Rittinger, K. Single-Domain Antibodies as Crystallization Chaperones to Enable Structure-Based Inhibitor Development for RBR E3 Ubiquitin Ligases. Cell Chem Biol, 27:83-, 2020 Cited by PubMed: 31813847 DOI: 10.1016/j.chembiol.2019.11.007 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.25 Å)

Structure validation