6S9J
Crystal structure of TfR1 mimicry in complex with GP1 from MACV
Summary for 6S9J
Entry DOI | 10.2210/pdb6s9j/pdb |
Descriptor | Pre-glycoprotein polyprotein GP complex, Transferrin receptor 1,Transferrin receptor 1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | immunotherapy, glycoprotein, viral, viral protein |
Biological source | Machupo virus (MACV) More |
Total number of polymer chains | 8 |
Total formula weight | 157978.86 |
Authors | Diskin, R.,Cohen-Dvashi, H. (deposition date: 2019-07-15, release date: 2020-01-15, Last modification date: 2024-01-24) |
Primary citation | Cohen-Dvashi, H.,Amon, R.,Agans, K.N.,Cross, R.W.,Borenstein-Katz, A.,Mateo, M.,Baize, S.,Padler-Karavani, V.,Geisbert, T.W.,Diskin, R. Rational design of universal immunotherapy for TfR1-tropic arenaviruses. Nat Commun, 11:67-67, 2020 Cited by PubMed: 31900422DOI: 10.1038/s41467-019-13924-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.698 Å) |
Structure validation
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