6S3Q

Structure of human excitatory amino acid transporter 3 (EAAT3) in complex with TFB-TBOA

Summary for 6S3Q

• Entry DOI: 10.2210/pdb6s3q/pdb
• EMDB information: 10094
• Descriptor: Excitatory amino acid transporter 3, (2~{S},3~{S})-2-azanyl-3-[[3-[[4-(trifluoromethyl)phenyl]carbonylamino]phenyl]methoxy]butanedioic acid, CHOLESTEROL HEMISUCCINATE, ... (4 entities in total)
• Functional Keywords: glutamate, aspartate transporter, cysteine, inhibitor complex, membrane protein, structural genomics, structural genomics consortium, sgc
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 3
• Total formula weight: 174349.98

Authors

Baronina, A.,Pike, A.C.W.,Yu, X.,Dong, Y.Y.,Shintre, C.A.,Tessitore, A.,Chu, A.,Rotty, B.,Venkaya, S.,Mukhopadhyay, S.,Borkowska, O.,Chalk, R.,Shrestha, L.,Burgess-Brown, N.A.,Edwards, A.M.,Arrowsmith, C.H.,Bountra, C.,Han, S.,Carpenter, E.P.,Structural Genomics Consortium (SGC) (deposition date: 2019-06-25, release date: 2020-07-08, Last modification date: 2024-05-22)

• Primary citation: Baronina, A.,Pike, A.C.W.,Han, S.,Carpenter, E.P.; Structure of human excitatory amino acid transporter 3 (EAAT3); TO BE PUBLISHED,

Experimental method

ELECTRON MICROSCOPY (3.34 Å)