6S2F

Cryo-EM structure of Ctf18-1-8 in complex with the catalytic domain of DNA polymerase epsilon (Class 2)

6S2F の概要

• エントリーDOI: 10.2210/pdb6s2f/pdb
• EMDBエントリー: 10088 10089
• 分子名称: DNA polymerase epsilon catalytic subunit A, Chromosome transmission fidelity protein 8, Chromosome transmission fidelity protein 18, ... (5 entities in total)
• 機能のキーワード: dna polymerase, pcna loader, protein complex, replication
• 由来する生物種: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 203931.69

構造登録者

Grabarczyk, D.B.,Song, B. (登録日: 2019-06-20, 公開日: 2020-07-08, 最終更新日: 2024-05-22)

• 主引用文献: Stokes, K.,Winczura, A.,Song, B.,Piccoli, G.,Grabarczyk, D.B.; Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication.; Nucleic Acids Res., 48:8128-8145, 2020; PubMed: 32585006; DOI: 10.1093/nar/gkaa541

実験手法

ELECTRON MICROSCOPY (5.8 Å)