6S1C

P3221 crystal form of the Ctf18-1-8/Pol2(1-528) complex

Summary for 6S1C

• Entry DOI: 10.2210/pdb6s1c/pdb
• Descriptor: DNA polymerase epsilon catalytic subunit A, Sister chromatid cohesion protein DCC1, Chromosome transmission fidelity protein 8, ... (4 entities in total)
• Functional Keywords: dna polymerase, pcna loader, protein complex, replication
• Biological source: Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast); More
• Total number of polymer chains: 8
• Total formula weight: 251398.10

Authors

Grabarczyk, D.B. (deposition date: 2019-06-18, release date: 2020-07-08, Last modification date: 2024-01-24)

• Primary citation: Stokes, K.,Winczura, A.,Song, B.,Piccoli, G.,Grabarczyk, D.B.; Ctf18-RFC and DNA Pol ε form a stable leading strand polymerase/clamp loader complex required for normal and perturbed DNA replication.; Nucleic Acids Res., 48:8128-8145, 2020; PubMed: 32585006; DOI: 10.1093/nar/gkaa541

Experimental method

X-RAY DIFFRACTION (6.1 Å)