6RXB

Crystal structure of TetR-Q116A from Acinetobacter baumannii AYE in complex with minocycline

Summary for 6RXB

• Entry DOI: 10.2210/pdb6rxb/pdb
• Descriptor: Tetracycline repressor protein class G, (4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE, MAGNESIUM ION, ... (8 entities in total)
• Functional Keywords: transcription regulation, transcription
• Biological source: Acinetobacter baumannii (strain AYE); More
• Total number of polymer chains: 4
• Total formula weight: 99002.92

Authors

Tam, H.K.,Himpich, S.,Pos, K.M. (deposition date: 2019-06-07, release date: 2020-07-15, Last modification date: 2024-01-24)

• Primary citation: Sumyk, M.,Himpich, S.,Foong, W.E.,Herrmann, A.,Pos, K.M.,Tam, H.K.; Binding of Tetracyclines to Acinetobacter baumannii TetR Involves Two Arginines as Specificity Determinants; Front Microbiol, 2021; DOI: 10.3389/fmicb.2021.711158

Experimental method

X-RAY DIFFRACTION (2.25 Å)