6RXB

Crystal structure of TetR-Q116A from Acinetobacter baumannii AYE in complex with minocycline

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, D)	Tetracycline repressor protein class G	polymer	214	24246.2	2	UniProt (B0VCI2)	Acinetobacter baumannii (strain AYE)
2	C, D (A, C)	Tetracycline repressor protein class G	polymer	214	24166.2	2	UniProt (B0VCI2)	Acinetobacter baumannii (strain AYE)
3	E, G, K, O (B, D, A, C)	(4S,4AS,5AR,12AS)-4,7-BIS(DIMETHYLAMINO)-3,10,12,12A-TETRAHYDROXY-1,11-DIOXO-1,4,4A,5,5A,6,11,12A-OCTAHYDROTETRACENE-2- CARBOXAMIDE	non-polymer		457.5	4	Chemie (MIY)
4	F, H, L, P (B, D, A, C)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	I, N (D, A)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
6	J (D)	SUCCINIC ACID	non-polymer		118.1	1	Chemie (SIN)
7	M (A)	1,2-ETHANEDIOL	non-polymer		62.1	1	Chemie (EDO)
8	Q, R, S, T (B, D, A, C)	water	water		18.0	128	Chemie (HOH)

Sequence modifications

B, D: 1 - 208 (UniProt: B0VCI2)

PDB	External Database	Details
Ala 116	Gln 116	engineered mutation
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag

A, C: 1 - 208 (UniProt: B0VCI2)

PDB	External Database	Details
Ala 116	Gln 116	engineered mutation
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	96824.7
Non-Polymers*	Number of molecules	12
	Total formula weight	2178.2
All*	Total formula weight	99002.9

*Water molecules are not included.