6RX1

Crystal structure of human syncytin 1 in post-fusion conformation

Summary for 6RX1

Entry DOI	10.2210/pdb6rx1/pdb
Descriptor	Syncytin-1, GLYCEROL, CHLORIDE ION, ... (4 entities in total)
Functional Keywords	human placental protein, membrane fusion, endogenous retrovirus, membrane protein, herv-w, syncytin
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	12741.68
Authors	Ruigrok, K.,Backovic, M.,Vaney, M.C.,Rey, F.A. (deposition date: 2019-06-07, release date: 2019-11-20, Last modification date: 2024-01-24)
Primary citation	Ruigrok, K.,Vaney, M.C.,Buchrieser, J.,Baquero, E.,Hellert, J.,Baron, B.,England, P.,Schwartz, O.,Rey, F.A.,Backovic, M. X-ray Structures of the Post-fusion 6-Helix Bundle of the Human Syncytins and their Functional Implications. J.Mol.Biol., 431:4922-4940, 2019 Cited by PubMed: 31711961 DOI: 10.1016/j.jmb.2019.10.020 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.1 Å)

Structure validation