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6RX1

Crystal structure of human syncytin 1 in post-fusion conformation

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Syncytin-1polymer10812614.11UniProt (Q9UQF0)Homo sapiens (Human)Endogenous retrovirus group W member 1,Env-W,Envelope polyprotein gPr73,Enverin,HERV-7q Envelope protein,HERV-W envelope protein,HERV-W_7q21.2 provirus ancestral Env polyprotein,Syncytin
2B
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
3C
(A)
CHLORIDE IONnon-polymer35.51Chemie (CL)
4D
(A)
waterwater18.070Chemie (HOH)
Sequence modifications
A: 342 - 435 (UniProt: Q9UQF0)
PDBExternal DatabaseDetails
Met 328-initiating methionine
His 329-expression tag
His 330-expression tag
His 331-expression tag
His 332-expression tag
His 333-expression tag
His 334-expression tag
Glu 335-expression tag
Asn 336-expression tag
Leu 337-expression tag
Tyr 338-expression tag
Phe 339-expression tag
Gln 340-expression tag
Ser 341-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight12614.1
Non-Polymers*Number of molecules2
Total formula weight127.5
All*Total formula weight12741.7
*Water molecules are not included.

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PDB entries from 2025-12-24

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