6RX1

Crystal structure of human syncytin 1 in post-fusion conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Syncytin-1	polymer	108	12614.1	1	UniProt (Q9UQF0) In PDB	Homo sapiens (Human)	Endogenous retrovirus group W member 1,Env-W,Envelope polyprotein gPr73,Enverin,HERV-7q Envelope protein,HERV-W envelope protein,HERV-W_7q21.2 provirus ancestral Env polyprotein,Syncytin
2	A	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
3	A	CHLORIDE ION	non-polymer		35.5	1	Chemie (CL)
4		water	water		18.0	70	Chemie (HOH)

Sequence modifications

A: 342 - 435 (UniProt: Q9UQF0)

PDB	External Database	Details
Met 328	-	initiating methionine
His 329	-	expression tag
His 330	-	expression tag
His 331	-	expression tag
His 332	-	expression tag
His 333	-	expression tag
His 334	-	expression tag
Glu 335	-	expression tag
Asn 336	-	expression tag
Leu 337	-	expression tag
Tyr 338	-	expression tag
Phe 339	-	expression tag
Gln 340	-	expression tag
Ser 341	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	12614.1
Non-Polymers*	Number of molecules	2
	Total formula weight	127.5
All*	Total formula weight	12741.7

*Water molecules are not included.