6RUV

Structure of the SCIN stabilized C3bBb convertase bound to Properdin and a the non-inhibitory nanobody hFPNb1

6RUV の概要

• エントリーDOI: 10.2210/pdb6ruv/pdb
• 分子名称: Nanobody hFPNb1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (12 entities in total)
• 機能のキーワード: innate immunity, complement, proteolytic enzyme, regulator, nanobody, immune system
• 由来する生物種: Lama glama; 詳細
• タンパク質・核酸の鎖数: 14
• 化学式量合計: 610525.62

構造登録者

Pedersen, D.V.,Andersen, G.R. (登録日: 2019-05-29, 公開日: 2019-08-21, 最終更新日: 2024-01-24)

• 主引用文献: Pedersen, D.V.,Gadeberg, T.A.F.,Thomas, C.,Wang, Y.,Joram, N.,Jensen, R.K.,Mazarakis, S.M.M.,Revel, M.,El Sissy, C.,Petersen, S.V.,Lindorff-Larsen, K.,Thiel, S.,Laursen, N.S.,Fremeaux-Bacchi, V.,Andersen, G.R.; Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.; Front Immunol, 10:2007-2007, 2019; PubMed: 31507604; DOI: 10.3389/fimmu.2019.02007

実験手法

X-RAY DIFFRACTION (6.15 Å)