6RUJ
Factor inhibiting HIF-1 alpha in complex with consensus ankyrin repeat domain-(d)3-hydroxy-Leu peptide
Summary for 6RUJ
Entry DOI | 10.2210/pdb6ruj/pdb |
Related | 4NR1 |
Descriptor | Hypoxia-inducible factor 1-alpha inhibitor, CONSENSUS ANKYRIN REPEAT DOMAIN-(D)3-hydroxy-Leu, ZINC ION, ... (6 entities in total) |
Functional Keywords | 2-og-dependent dioxygenase, oxidoreductase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 2 |
Total formula weight | 42452.85 |
Authors | Nakashima, Y.,McDonough, M.A.,Schofield, C.J. (deposition date: 2019-05-28, release date: 2020-07-08, Last modification date: 2024-01-24) |
Primary citation | Choi, H.,Hardy, A.,Leissing, T.M.,Chowdhury, R.,Ge, W.,Markoulides, M.,Scotti, J.S.,Thorbjornsrud, H.,Nakashima, Y.,Kang, D.,Hong, S.,Lee, J.,Park, H.,McDonough, M.A.,Schofield, C.J. A human protein hydroxylase that accepts D-residues Commun Chem, 2020 Cited by DOI: 10.1038/s42004-020-0290-5PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.42 Å) |
Structure validation
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