6RU5

human complement C3 in complex with the hC3Nb1 nanobody

6RU5 の概要

• エントリーDOI: 10.2210/pdb6ru5/pdb
• 分子名称: Complement C3, hC3Nb1, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: innate immunity, complement c3, antibody, nanobody, immune system
• 由来する生物種: Lama glama (llama); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 200040.14

構造登録者

Jensen, R.K.,Andersen, G.R. (登録日: 2019-05-27, 公開日: 2019-08-21, 最終更新日: 2024-01-24)

• 主引用文献: Pedersen, D.V.,Gadeberg, T.A.F.,Thomas, C.,Wang, Y.,Joram, N.,Jensen, R.K.,Mazarakis, S.M.M.,Revel, M.,El Sissy, C.,Petersen, S.V.,Lindorff-Larsen, K.,Thiel, S.,Laursen, N.S.,Fremeaux-Bacchi, V.,Andersen, G.R.; Structural Basis for Properdin Oligomerization and Convertase Stimulation in the Human Complement System.; Front Immunol, 10:2007-2007, 2019; PubMed: 31507604; DOI: 10.3389/fimmu.2019.02007

実験手法

X-RAY DIFFRACTION (3.9 Å)