6ROE

Human Carbonic Anhydrase II in complex with fluorinated benzenesulfonamide

Summary for 6ROE

Entry DOI	10.2210/pdb6roe/pdb
Related	6RIT 6RJJ 6RKN 6RNP
Descriptor	Carbonic anhydrase 2, beta-D-glucopyranose, alpha-D-glucopyranose, ... (8 entities in total)
Functional Keywords	inhibitor, complex, co2 conversion, lyase
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	31356.55
Authors	Gloeckner, S.,Heine, A.,Klebe, G. (deposition date: 2019-05-12, release date: 2020-04-15, Last modification date: 2024-01-24)
Primary citation	Glockner, S.,Ngo, K.,Wagner, B.,Heine, A.,Klebe, G. The Influence of Varying Fluorination Patterns on the Thermodynamics and Kinetics of Benzenesulfonamide Binding to Human Carbonic Anhydrase II. Biomolecules, 10:-, 2020 Cited by PubMed: 32230853 DOI: 10.3390/biom10040509 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (0.939 Å)

Structure validation