6RMV

The crystal structure of a TRP channel peptide bound to a G protein beta gamma heterodimer

6RMV の概要

• エントリーDOI: 10.2210/pdb6rmv/pdb
• 分子名称: Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Transient receptor potential cation channel, subfamily M, member 3, ... (5 entities in total)
• 機能のキーワード: g protein, trp channel, inhibitor, protein binding
• 由来する生物種: Mus musculus (Mouse); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 47286.39

構造登録者

Gruss, F.,Oberwinkler, J.,Ulens, C. (登録日: 2019-05-07, 公開日: 2020-10-14, 最終更新日: 2024-01-24)

• 主引用文献: Behrendt, M.,Gruss, F.,Enzeroth, R.,Dembla, S.,Zhao, S.,Crassous, P.A.,Mohr, F.,Nys, M.,Louros, N.,Gallardo, R.,Zorzini, V.,Wagner, D.,Economou, A.,Rousseau, F.,Schymkowitz, J.,Philipp, S.E.,Rohacs, T.,Ulens, C.,Oberwinkler, J.; The structural basis for an on-off switch controlling G beta gamma-mediated inhibition of TRPM3 channels.; Proc.Natl.Acad.Sci.USA, 117:29090-29100, 2020; PubMed: 33122432; DOI: 10.1073/pnas.2001177117

実験手法

X-RAY DIFFRACTION (1.94 Å)