6RMG

Structure of PTCH1 bound to a modified Hedgehog ligand ShhN-C24II

6RMG の概要

• エントリーDOI: 10.2210/pdb6rmg/pdb
• EMDBエントリー: 4936
• 分子名称: Protein patched homolog 1,GFP-like fluorescent chromoprotein FP506, related, Sonic hedgehog protein, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: patched, ptch1, hedgehog, shhn, membrane protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 203194.08

構造登録者

Korkhov, V.M.,Qi, C. (登録日: 2019-05-06, 公開日: 2019-10-09, 最終更新日: 2020-07-29)

• 主引用文献: Qi, C.,Di Minin, G.,Vercellino, I.,Wutz, A.,Korkhov, V.M.; Structural basis of sterol recognition by human hedgehog receptor PTCH1.; Sci Adv, 5:eaaw6490-eaaw6490, 2019; PubMed: 31555730; DOI: 10.1126/sciadv.aaw6490

実験手法

ELECTRON MICROSCOPY (3.4 Å)