6RIR

Crystal structure of phosphorylated Rab8a in complex with the Rab-binding domain of RILPL2

6RIR の概要

• エントリーDOI: 10.2210/pdb6rir/pdb
• 分子名称: Ras-related protein Rab-8A, RILP-like protein 2, GUANOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
• 機能のキーワード: membrane trafficking, rab gtpase, effector, signaling protein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 54037.42

構造登録者

Waschbusch, D.,Purlyte, E.,Alessi, D.R.,Khan, A.R. (登録日: 2019-04-25, 公開日: 2020-01-29, 最終更新日: 2024-01-24)

• 主引用文献: Waschbusch, D.,Purlyte, E.,Pal, P.,McGrath, E.,Alessi, D.R.,Khan, A.R.; Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2.; Structure, 28:406-417.e6, 2020; PubMed: 32017888; DOI: 10.1016/j.str.2020.01.005

実験手法

X-RAY DIFFRACTION (1.767 Å)