6RFU

In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of ATP and GMP as genuine co-factors

6RFU の概要

• エントリーDOI: 10.2210/pdb6rfu/pdb
• 分子名称: Inosine-5'-monophosphate dehydrogenase, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-MONOPHOSPHATE, ... (4 entities in total)
• 機能のキーワード: imp dehydrogenase, trypanosoma brucei, in cellulo crystallization, fel, immunosuppressant
• 由来する生物種: Trypanosoma brucei brucei
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 113300.16

構造登録者

Nass, K.,Redecke, L.,Perbandt, M.,Yefanov, O.,Gabdulkhakov, A.,Duszenko, M.,Chapman, H.N.,Betzel, C. (登録日: 2019-04-16, 公開日: 2020-02-19, 最終更新日: 2024-01-24)

• 主引用文献: Nass, K.,Redecke, L.,Perbandt, M.,Yefanov, O.,Klinge, M.,Koopmann, R.,Stellato, F.,Gabdulkhakov, A.,Schonherr, R.,Rehders, D.,Lahey-Rudolph, J.M.,Aquila, A.,Barty, A.,Basu, S.,Doak, R.B.,Duden, R.,Frank, M.,Fromme, R.,Kassemeyer, S.,Katona, G.,Kirian, R.,Liu, H.,Majoul, I.,Martin-Garcia, J.M.,Messerschmidt, M.,Shoeman, R.L.,Weierstall, U.,Westenhoff, S.,White, T.A.,Williams, G.J.,Yoon, C.H.,Zatsepin, N.,Fromme, P.,Duszenko, M.,Chapman, H.N.,Betzel, C.; In cellulo crystallization of Trypanosoma brucei IMP dehydrogenase enables the identification of genuine co-factors.; Nat Commun, 11:620-620, 2020; PubMed: 32001697; DOI: 10.1038/s41467-020-14484-w

実験手法

X-RAY DIFFRACTION (2.8 Å)