6RCT
Crystal structure of CLK3 in complex with T3-CLK
Summary for 6RCT
Entry DOI | 10.2210/pdb6rct/pdb |
Descriptor | Dual specificity protein kinase CLK3, 4-[2-methyl-1-(4-methylpiperazin-1-yl)-1-oxidanylidene-propan-2-yl]-~{N}-(6-pyridin-4-ylimidazo[1,2-a]pyridin-2-yl)benzamide, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | clk3, splicing kinase, probe, kinase inhibitor, structural genomics, structural genomics consortium, sgc, transferase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 86222.66 |
Authors | Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2019-04-11, release date: 2019-05-01, Last modification date: 2024-01-24) |
Primary citation | Chaikuad, A.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) Crystal structure of CLK3 in complex with TP003 To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.32 Å) |
Structure validation
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