6RBI

Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol

Summary for 6RBI

• Entry DOI: 10.2210/pdb6rbi/pdb
• Descriptor: Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ... (8 entities in total)
• Functional Keywords: epigenetics, kdm, lysine demethylase, chromatin, 2-oxoglutarate-dependent oxygenase, tetrazole, oxidoreductase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 1
• Total formula weight: 56245.75

Authors

Johansson, C.,Newman, J.A.,Kawamura, A.,Schofield, C.J.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T. (deposition date: 2019-04-10, release date: 2020-05-13, Last modification date: 2024-01-24)

• Primary citation: Johansson, C.,Newman, J.A.,Kawamura, A.,Schofield, C.J.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T.; Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.21 Å)