6RBI

Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol

6RBI の概要

• エントリーDOI: 10.2210/pdb6rbi/pdb
• 分子名称: Lysine-specific demethylase 5B,Lysine-specific demethylase 5B, ZINC ION, MANGANESE (II) ION, ... (8 entities in total)
• 機能のキーワード: epigenetics, kdm, lysine demethylase, chromatin, 2-oxoglutarate-dependent oxygenase, tetrazole, oxidoreductase
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 56245.75

構造登録者

Johansson, C.,Newman, J.A.,Kawamura, A.,Schofield, C.J.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T. (登録日: 2019-04-10, 公開日: 2020-05-13, 最終更新日: 2024-01-24)

• 主引用文献: Johansson, C.,Newman, J.A.,Kawamura, A.,Schofield, C.J.,Arrowsmith, C.H.,Bountra, C.,Edwards, A.,Oppermann, U.C.T.; Crystal structure of KDM5B in complex with 5-(1H-tetrazol-5-yl)quinolin-8-ol; To Be Published,

実験手法

X-RAY DIFFRACTION (2.21 Å)