6RB7

Ruminococcus gnavus sialic acid aldolase catalytic lysine mutant

Summary for 6RB7

• Entry DOI: 10.2210/pdb6rb7/pdb
• Descriptor: Putative N-acetylneuraminate lyase, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLYCEROL, ... (7 entities in total)
• Functional Keywords: neu5ac, sialic acid, aldolase, lyase, ruminococcus gnavus
• Biological source: [Ruminococcus] gnavus ATCC 29149
• Total number of polymer chains: 4
• Total formula weight: 150034.11

Authors

Owen, C.D.,Bell, A.,Juge, N.,Walsh, M.A. (deposition date: 2019-04-09, release date: 2019-09-25, Last modification date: 2024-01-24)

• Primary citation: Bell, A.,Brunt, J.,Crost, E.,Vaux, L.,Nepravishta, R.,Owen, C.D.,Latousakis, D.,Xiao, A.,Li, W.,Chen, X.,Walsh, M.A.,Claesen, J.,Angulo, J.,Thomas, G.H.,Juge, N.; Elucidation of a sialic acid metabolism pathway in mucus-foraging Ruminococcus gnavus unravels mechanisms of bacterial adaptation to the gut.; Nat Microbiol, 4:2393-2404, 2019; PubMed: 31636419; DOI: 10.1038/s41564-019-0590-7

Experimental method

X-RAY DIFFRACTION (1.6 Å)