6R4L

Crystal structure of S. cerevisia Niemann-Pick type C protein NCR1

Summary for 6R4L

Entry DOI	10.2210/pdb6r4l/pdb
Descriptor	NPC intracellular cholesterol transporter 1-related protein 1, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ERGOSTEROL, ... (4 entities in total)
Functional Keywords	vacuole, ergosterol, lipid transport, membrane protein
Biological source	Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Total number of polymer chains	1
Total formula weight	137503.99
Authors	Winkler, M.B.L.,Kidmose, R.T.,Pedersen, B.P. (deposition date: 2019-03-22, release date: 2019-09-25, Last modification date: 2024-01-24)
Primary citation	Winkler, M.B.L.,Kidmose, R.T.,Szomek, M.,Thaysen, K.,Rawson, S.,Muench, S.P.,Wustner, D.,Pedersen, B.P. Structural Insight into Eukaryotic Sterol Transport through Niemann-Pick Type C Proteins. Cell, 179:485-497.e18, 2019 Cited by PubMed: 31543266 DOI: 10.1016/j.cell.2019.08.038 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.5 Å)

Structure validation